Barkley Pathophysiology, Pharmacology, and Physical (3P) Assessment Practice Exam

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A patient diagnosed with acute inflammatory demyelinating polyneuropathy should be assessed for what condition?

Cerebrospinal fluid high in protein (500 mg/dl) without cellular abnormality

The condition to be assessed in a patient diagnosed with acute inflammatory demyelinating polyneuropathy (AIDP) is the presence of cerebrospinal fluid that is high in protein (500 mg/dl) without cellular abnormality. This finding is characteristic of AIDP, which is often associated with the Guillain-Barré syndrome.

In AIDP, the immune system attacks the peripheral nerves, leading to demyelination. When cerebrospinal fluid is analyzed, a high protein concentration typically indicates an inflammatory process, while the absence of significant white blood cells (pleocytosis) helps distinguish it from other conditions like infections or malignancies. This combination is critical for the diagnosis of AIDP, which is predominantly a peripheral nervous system disorder.

The other options, while related to various conditions and symptoms, do not reflect the typical findings or assessments relevant specifically to AIDP. For example, decreased levels of acetylcholine are more related to conditions like myasthenia gravis rather than AIDP. Similarly, asymmetric paralysis is not a defining feature of this condition; patients often experience symmetrical weakness. Lastly, demyelination of the central nervous system nerves pertains to conditions like multiple sclerosis rather than AIDP,

Decreased levels of acetylcholine

Asymmetric paralysis

Demyelination of the central nervous system nerves

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